3rjw
From Proteopedia
Crystal structure of histone lysine methyltransferase g9a with an inhibitor
Template:ABSTRACT PUBMED 21743462
About this Structure
3rjw is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3nni. Full crystallographic information is available from OCA.
Reference
- Vedadi M, Barsyte-Lovejoy D, Liu F, Rival-Gervier S, Allali-Hassani A, Labrie V, Wigle TJ, Dimaggio PA, Wasney GA, Siarheyeva A, Dong A, Tempel W, Wang SC, Chen X, Chau I, Mangano TJ, Huang XP, Simpson CD, Pattenden SG, Norris JL, Kireev DB, Tripathy A, Edwards A, Roth BL, Janzen WP, Garcia BA, Petronis A, Ellis J, Brown PJ, Frye SV, Arrowsmith CH, Jin J. A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol. 2011 Jul 10;7(8):566-74. doi: 10.1038/nchembio.599. PMID:21743462 doi:10.1038/nchembio.599
Categories: Histone-lysine N-methyltransferase | Homo sapiens | Allali-Hassani, A. | Arora, K. | Arrowsmith, C H. | Barsyte, D. | Bochkarev, A. | Bountra, C. | Brown, P J. | Chau, I. | Chavda, N. | Chen, X. | Dong, A. | Edwards, A M. | Frye, S V. | Hajian, T. | Herold, J M. | Jin, J. | Kireev, D B. | Liu, F. | SGC, Structural Genomics Consortium. | Senisterra, G. | Siarheyeva, A. | Tempel, W. | Vedadi, M. | Wasney, G A. | Weigelt, J. | Chemical probe | Methyltransferase inhibitor | Sgc | Structural genomics consortium | Transferase-transferase inhibitor complex
