3tfn

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Image:3tfn.png

Template:STRUCTURE 3tfn

Crystal structure of dehydrosqualene synthase (crtm) from s. aureus complexed with bph-1183

Template:ABSTRACT PUBMED 22290830

About this Structure

3tfn is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Lin FY, Zhang Y, Hensler M, Liu YL, Chow OA, Zhu W, Wang K, Pang R, Thienphrapa W, Nizet V, Oldfield E. Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics. ChemMedChem. 2012 Apr;7(4):561-4. doi: 10.1002/cmdc.201100589. Epub 2012 Jan 30. PMID:22290830 doi:10.1002/cmdc.201100589

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OCA

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