4dhf
From Proteopedia
Structure of Aurora A mutant bound to Biogenidec cpd 15
Template:ABSTRACT PUBMED 22607669
About this Structure
4dhf is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Le Brazidec JY, Pasis A, Tam B, Boykin C, Wang D, Marcotte DJ, Claassen G, Chong JH, Chao J, Fan J, Nguyen K, Silvian L, Ling L, Zhang L, Choi M, Teng M, Pathan N, Zhao S, Li T, Taveras A. Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4033-7. Epub 2012 Apr 25. PMID:22607669 doi:10.1016/j.bmcl.2012.04.085
