452d

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Image:452d.png

Template:STRUCTURE 452d

ACRIDINE BINDING TO DNA

About this Structure

452D is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ. Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution. J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960 doi:10.1021/jm980479u

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