4ags
From Proteopedia
Leishmania TDR1 - a unique trimeric glutathione transferase
Template:ABSTRACT PUBMED 22753509
About this Structure
4ags is a 3 chain structure with sequence from Leishmania infantum. Full crystallographic information is available from OCA.
Reference
- Fyfe PK, Westrop GD, Silva AM, Coombs GH, Hunter WN. Leishmania TDR1 structure, a unique trimeric glutathione transferase capable of deglutathionylation and antimonial prodrug activation. Proc Natl Acad Sci U S A. 2012 Jul 2. PMID:22753509 doi:10.1073/pnas.1202593109
- Denton H, McGregor JC, Coombs GH. Reduction of anti-leishmanial pentavalent antimonial drugs by a parasite-specific thiol-dependent reductase, TDR1. Biochem J. 2004 Jul 15;381(Pt 2):405-12. PMID:15056070 doi:10.1042/BJ20040283
