4dfl

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Image:4dfl.jpg

Template:STRUCTURE 4dfl

Crystal structure of spleen tyrosine kinase complexed with a sulfonamidopyrazine piperidine inhibitor

Template:ABSTRACT PUBMED 22425453

About this Structure

4dfl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Forns P, Esteve C, Taboada L, Alonso JA, Orellana A, Maldonado M, Carreno C, Ramis I, Lopez M, Miralpeix M, Vidal B. Pyrazine-based Syk kinase inhibitors. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2784-8. Epub 2012 Mar 2. PMID:22425453 doi:10.1016/j.bmcl.2012.02.087

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