4dem

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Image:4dem.png

Template:STRUCTURE 4dem

Crystal structure of human FPPS in complex with YS_04_70

Template:ABSTRACT PUBMED 22390415

About this Structure

4dem is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lin YS, Park J, De Schutter JW, Huang XF, Berghuis AM, Sebag M, Tsantrizos YS. Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. J Med Chem. 2012 Mar 19. PMID:22390415 doi:10.1021/jm201657x

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OCA

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