4afe
From Proteopedia
Nek2 bound to hybrid compound 21
Template:ABSTRACT PUBMED 22404346
About this Structure
4afe is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Innocenti P, Cheung KM, Solanki S, Mas-Droux C, Rowan F, Yeoh S, Boxall K, Westlake M, Pickard L, Hardy T, Baxter JE, Aherne GW, Bayliss R, Fry AM, Hoelder S. Design of potent and selective hybrid inhibitors of the mitotic kinase nek2: structure-activity relationship, structural biology, and cellular activity. J Med Chem. 2012 Apr 12;55(7):3228-41. Epub 2012 Mar 23. PMID:22404346 doi:10.1021/jm201683b
