4duh

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Image:4duh.png

Template:STRUCTURE 4duh

Crystal structure of 24 kDa domain of E. coli DNA gyrase B in complex with small molecule inhibitor

Template:ABSTRACT PUBMED 22731783

About this Structure

4duh is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Brvar M, Perdih A, Renko M, Anderluh G, Turk D, Solmajer T. Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors. J Med Chem. 2012 Jul 26;55(14):6413-26. Epub 2012 Jul 5. PMID:22731783 doi:10.1021/jm300395d

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