3u7f

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Template:STRUCTURE 3u7f

Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp)

Template:ABSTRACT PUBMED 22171004

About this Structure

3u7f is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Coquelle N, Havali-Shahriari Z, Bernstein N, Green R, Glover JN. Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21022-7. Epub 2011 Dec 14. PMID:22171004 doi:10.1073/pnas.1112036108
  • Bernstein NK, Williams RS, Rakovszky ML, Cui D, Green R, Karimi-Busheri F, Mani RS, Galicia S, Koch CA, Cass CE, Durocher D, Weinfeld M, Glover JN. The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase. Mol Cell. 2005 Mar 4;17(5):657-70. PMID:15749016 doi:10.1016/j.molcel.2005.02.012

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