3u8w

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Image:3u8w.jpg

Template:STRUCTURE 3u8w

Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Triazolopyridazinone inhibitor

Template:ABSTRACT PUBMED 22196117

About this Structure

3u8w is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Herberich B, Jackson C, Wurz RP, Pettus LH, Sherman L, Liu Q, Henkle B, Saris CJ, Wong LM, Chmait S, Lee MR, Mohr C, Hsieh F, Tasker AS. Identification of triazolopyridazinones as potent p38alpha inhibitors. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1226-9. Epub 2011 Nov 23. PMID:22196117 doi:10.1016/j.bmcl.2011.11.067

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