1d96

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Image:1d96.gif

1d96, resolution 2.000Å

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MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA

Overview

The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA hybrid segments surrounding a central region of double helical DNA; its molecular structure has been solved by X-ray analysis. All three parts of the molecule adopt a conformation which is close to that seen in the 11-fold RNA double helix. The conformation of the ribonucleotides is partly determined by water molecules bridging between the ribose O2' hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no structural discontinuities. However, the central DNA TATA sequence has some structural irregularities.

About this Structure

1D96 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:6181416

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