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4k1s

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Template:STRUCTURE 4k1s

Contents

Gly-Ser-SplB protease from Staphylococcus aureus at 1.96 A resolution

Function

[SPLB_STAA8] Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln.[1]

About this Structure

4k1s is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Dubin G, Stec-Niemczyk J, Kisielewska M, Pustelny K, Popowicz GM, Bista M, Kantyka T, Boulware KT, Stennicke HR, Czarna A, Phopaisarn M, Daugherty PS, Thogersen IB, Enghild JJ, Thornberry N, Dubin A, Potempa J. Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln. J Mol Biol. 2008 May 30;379(2):343-56. Epub 2008 Apr 3. PMID:18448121 doi:10.1016/j.jmb.2008.03.059

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