| Structural highlights
4ngv is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
| | Ligands: | ,
| | Related: | 4neb, 4nfv, 4ng1, 4ng8, 4ngi, 4ngj, 4ngk, 4ngl, 4ngo, 4ngy, 4ngz |
| Activity: | Lysozyme, with EC number 3.2.1.17 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Publication Abstract from PubMed
The influence of salt nature and concentration on tetragonal lysozyme chloride crystal solubility is presented for a set of mono-, di- and trivalent cations (Cs(+), Rb(+), Mn(2+), Co(2+) and Yb(3+)). The results show that cations have as strong an effect on protein solubility as anions and that they present their own particular effects as co-ions. Indeed, after decreasing at low ionic strength, lysozyme solubility increases with high concentration of polyvalent cations, probably due to co-ion binding and therefore the concomitant increase of the net charge of the protein-salt complex. These new results are discussed in order to progress in the understanding of the crystallisation process at the atomic level.
Strong and specific effects of cations on lysozyme chloride solubility.,Benas P, Legrand L, Ries-Kautt M Acta Crystallogr D Biol Crystallogr. 2002 Oct;58(Pt 10 Pt 1):1582-7. Epub 2002, Sep 26. PMID:12351866[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Benas P, Legrand L, Ries-Kautt M. Strong and specific effects of cations on lysozyme chloride solubility. Acta Crystallogr D Biol Crystallogr. 2002 Oct;58(Pt 10 Pt 1):1582-7. Epub 2002, Sep 26. PMID:12351866
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