ATP synthase

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Template:STRUCTURE 1ho8

ATP synthase (ATPS) also known as V-ATPase, catalyzes the synthesis of ATP from ADP and phosphate. In mitochondria, the F1F0 ATPS contains the F0 membranal part (F1-ATPS). Its subunits are named by Greek or Roman letters. The images at the left and at the right correspond to one representative ATPS, i.e. the crystal structure of yeast yATPS, subunit H (1ho8).

Contents 1 3D Structures of ATP synthase 1.1 V-ATPase 1.2 V-ATPase subunit A 1.3 V-ATPase subunit B 1.4 V-ATPase subunit C 1.5 V-ATPase subunit E 1.6 V-ATPase subunit F 1.7 V-ATPase subunit G 1.8 V-ATPase subunit H 1.9 V-ATPase subunit K 1.10 V-ATPase subunit I 1.11 F1F0 ATPase 1.12 F1F0 ATPase α subunit 1.13 F1F0 ATPase β subunit 1.14 F1F0 ATPase γ subunit 1.15 F1F0 ATPase δ subunit 1.16 F1F0 ATPase ε subunit 1.17 F1F0 ATPase α, β subunits 1.18 F1F0 ATPase α,γ subunits 1.19 F1F0 ATPase α, δ subunits 1.20 F1F0 ATPase β, δ subunits 1.21 F1F0 ATPase γ, ε subunits 1.22 F1F0 ATPase α,β,γ,δ subunits 1.23 F1F0 ATPase α,β,γ,ε subunits 1.24 F1F0 ATPase α, β, γ, δ, ε subunits 1.25 F1F0 ATPase α,β,γ,δ,ε,9,B,D,6,O subunits

3D Structures of ATP synthase

Updated on 14-August-2014

V-ATPase

V-ATPase subunit A

3i4l - PhATPS subunit A+AMPPNP
3mfy, 3m4y, 3nd8, 3nd9, 3p20, 3qg1, 3qia, 3qjy, 3sdz, 3se0 - PhATPS subunit A mutant)
3i72, 3i73, 3ikj - TtATPS subunit A (mutant)

V-ATPase subunit B

2c61 - MmATPS subunit B – Methanosarcina mazei
2rkw, 3b2q, 3ssa, 3tgw, 3tiv - MmATPS subunit B (mutant)
3dsr - MmATPS subunit B+ADP
3eiu - MmATPS subunit B+ATP

V-ATPase subunit C

1u7l, 3u2f, 3u2y, 3u32, 3ud0 - yATPS subunit C
3v3c - ATPS subunit C - pea
1ijp, 1l6t – EcF1-ATPS subunit C (mutant) – Escherichia coli - NMR
1r5z, 1v9m - TtATPS subunit C – Thermus thermophilus
3lg8 - MtATPS subunit C C-terminal
2w5j - sATPS subunit C - spinach
2wie, 2xqs, 2xqt, 2xqu - ATPS subunit C – Arthrospira platensis
3zk1, 3zk2 - ATPS subunit C – Fusobacterium nucleatum

V-ATPase subunit E

2kz9 – yATPase subunit E
2dm9, 2dma, 4dt0 - PhATPS subunit E – Pyrococcus horikoshii
2kk7 - MjATPS subunit E – Methanocaldococcus jannaschii
3v6i – TtATPS subunit E + VAPC

V-ATPase subunit F

2qai - ATPS subunit F – Pyrococcus furiosus
2i4r - ATPS subunit F – Archaeoglobus fulgidus
2ov6 - MmATPS subunit F - NMR
2d00 - TtATPS subunit F
4ix9 – yATP subunit F (mutant)

V-ATPase subunit G

2k88 - yATPS subunit G - NMR

V-ATPase subunit H

1ho8 – yATPS subunit H – yeast

V-ATPase subunit K

2bl2, 2cyd - ATPS subunit K – Enterococcus hirae

V-ATPase subunit I

3rrk – ATPS subunit I N terminal – Meiothermus ruber

4dl0, 4efa - yATPase subunits C,G,E
3w3a - yATPS subunit A,B,D,F
3a5c, 3a5d - TtATPS subunit A,B,D,F
3gqb - TtATPS subunit A (mutant),B (mutant)
3k5b - TtATPS subunit E (mutant)+C
1fx0 – sATPS subunit A,B

F1F0 ATPase

F1F0 ATPase α subunit

2jmx - bF1-ATPS+subunit O
2r9v - F1-ATPS – Thermotoga maritima

F1F0 ATPase β subunit

1b9u – EcF1-ATPS membrane domain – Escherichia coli -NMR
1l2p – EcF1-ATPS dimerization domain
2khk - EcF1-ATPS fragment – NMR
1pyv - F1-ATPS – NMR – tobacco

F1F0 ATPase γ subunit

1wu0 – BsATPS – NMR
1a91, 1c0v, 1aty, 1c99 - EcF1-ATPS – NMR
2wgm, 1yce – F0-ATPS – Ilyobacter tartaricus
2x2v – F0-ATPS – Bacillus pseudofirmus

F1F0 ATPase δ subunit

1abv – EcF1-ATPS N terminal – NMR

F1F0 ATPase ε subunit

2rq6, 2rq7 - F1-ATPS – Thermosynechococcus elongatus
1abv, 1aqt– EcF1-ATPS (mutant)
1bsh, 1bsn – EcF1-ATPS – NMR
2e5t, 2e5u – BsF1-ATPS C terminal – NMR
2e5y – BsF1-ATPS

F1F0 ATPase α, β subunits

1sky – BsF1-ATPS – Bacillus sp. Ps3

F1F0 ATPase α,γ subunits

1c17 – EcF1-ATPS – NMR

F1F0 ATPase α, δ subunits

2a7u – EcF1-ATPS N termini – NMR

F1F0 ATPase β, δ subunits

2cly – bF1-ATPS + ATPS coupling factor

F1F0 ATPase γ, ε subunits

1fs0 – EcF1-ATPS

1ohh, 2jiz – bF1-ATPS+ IF1 inhibitor – bovine
1e1q, 2w6e, 2w6f, 2w6g, 2w6h, 2w6i, 2w6j - bF1-ATPS
1e1r - bF1-ATPS+Mg+ADP+AlF4
1w0j, 1w0k - bF1-ATPS+BeF3
1nbm - bF1-ATPS+nitrobenzofurazan
1mab, 2f43 - F1-ATPS – rat

F1F0 ATPase α,β,γ,δ subunits

1qo1 - yF1-ATPS + protein 9

F1F0 ATPase α,β,γ,ε subunits

1jnv - EcF1-ATPS
3oaa – EcF1-ATPS (mutant)
2qe7 – F1-ATPS – Bacillus

F1F0 ATPase α, β, γ, δ, ε subunits

4asu, 2jdi, 2jj1, 2jj2 - bF1-ATPS
2v7q, 1e79, 2ck3 - bF1-ATPS+inhibitor
2xnd, 2xok - bF1-ATPS+ATPS lipid-binding protein
2wpd, 2wss - yF1-ATPS+subunit 9+Mg+ADP+ATP
3oe7, 3oee, 3oeh, 3ofn - yF1-ATPS (mutant)
3fks, [[3zry], 2hld] - yF1-ATPS
2zia - bF1-ATPS+inhibitor protein
3j0j – TtATPS α,β,γ,δ,ε,ζ - Cryo EM

F1F0 ATPase α,β,γ,δ,ε,9,B,D,6,O subunits

4b2q – yATPase subunits α,β,γ,δ,ε +9,B,D,6,O – Cryo EM

1bmf - bF1-ATPS
3dze – bF1-ATPS subunit S
1cow - bF1-ATPS+aurovertin B
4f4s – yATPase subunit 9 + oligomycin