1i7c

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spinqualitylabelsall models PDB ID 1i7c Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1i7c, resolution 2.40Å ()
Ligands:	,
Non-Standard Residues:
Activity:	Adenosylmethionine decarboxylase, with EC number 4.1.1.50
Related:	1jen, 1i72, 1i79, 1i7b, 1i7m
Structural annotation: Resources: CATH : 1I7Ca00 InterPro : Ipr001985 Pfam : PF01536 SCOP : d1i7c.1 UniProt : P17707
Functional annotation: Cellular component: cellular_component Biological process: spermidine biosynthetic process spermine biosynthetic process Molecular function: adenosylmethionine decarboxylase activity carboxy-lyase activity lyase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Contents 1 HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COMPLEXED WITH METHYLGLYOXAL BIS-(GUANYLHYDRAZONE) 2 About this Structure 3 See Also 4 Reference

HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COMPLEXED WITH METHYLGLYOXAL BIS-(GUANYLHYDRAZONE)

Template:ABSTRACT PUBMED 11583147

About this Structure

1i7c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• S-adenosylmethionine decarboxylase

Reference

• Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE. The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase. Biochemistry. 2001 Aug 14;40(32):9484-94. PMID:11583147