1jlb
From Proteopedia
Contents |
CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE
Template:ABSTRACT PUBMED 11575933
About this Structure
1jlb is a 2 chain structure with sequence from Hiv-1 m:b_hxb2r. The September 2002 RCSB PDB Molecule of the Month feature on Reverse Transcriptase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_9. Full crystallographic information is available from OCA.
See Also
Reference
- Ren J, Nichols C, Bird L, Chamberlain P, Weaver K, Short S, Stuart DI, Stammers DK. Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors. J Mol Biol. 2001 Sep 28;312(4):795-805. PMID:11575933 doi:http://dx.doi.org/10.1006/jmbi.2001.4988
Categories: Hiv-1 m:b hxb2r | RCSB PDB Molecule of the Month | RNA-directed DNA polymerase | Reverse Transcriptase | Bird, L. | Chamberlain, P. | Nichols, C. | Ren, J. | Short, S. | Stammers, D K. | Stuart, D I. | Weaver, K. | Aid | Drug design | Drug resistance mutation | Hiv-1 reverse transcriptase | Nevirapine | Non-nucleoside inhibitor | Transferase
