1t05

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Template:STRUCTURE 1t05

Contents 1 HIV-1 reverse transcriptase crosslinked to template-primer with tenofovir-diphosphate bound as the incoming nucleotide substrate 2 About this Structure 3 See Also 4 Reference

HIV-1 reverse transcriptase crosslinked to template-primer with tenofovir-diphosphate bound as the incoming nucleotide substrate

Template:ABSTRACT PUBMED 15107837

About this Structure

1t05 is a 4 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

• Reverse transcriptase

Reference

• Tuske S, Sarafianos SG, Clark AD Jr, Ding J, Naeger LK, White KL, Miller MD, Gibbs CS, Boyer PL, Clark P, Wang G, Gaffney BL, Jones RA, Jerina DM, Hughes SH, Arnold E. Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir. Nat Struct Mol Biol. 2004 May;11(5):469-74. Epub 2004 Apr 25. PMID:15107837 doi:10.1038/nsmb760