1z76
From Proteopedia
Contents |
Crystal structure of an acidic phospholipase A2 (BthA-I) from Bothrops jararacussu venom complexed with p-bromophenacyl bromide
Template:ABSTRACT PUBMED 16301802
About this Structure
1z76 is a 2 chain structure with sequence from Bothrops jararacussu. Full crystallographic information is available from OCA.
See Also
Reference
- Magro AJ, Takeda AA, Soares AM, Fontes MR. Structure of BthA-I complexed with p-bromophenacyl bromide: possible correlations with lack of pharmacological activity. Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1670-7. Epub 2005, Nov 19. PMID:16301802 doi:10.1107/S0907444905029598
- Takeda AA, dos Santos JI, Marcussi S, Silveira LB, Soares AM, Fontes MR. Crystallization and preliminary X-ray diffraction analysis of an acidic phospholipase A(2) complexed with p-bromophenacyl bromide and alpha-tocopherol inhibitors at 1.9- and 1.45-A resolution. Biochim Biophys Acta. 2004 Jun 1;1699(1-2):281-4. PMID:15158738 doi:10.1016/j.bbapap.2004.02.005
- Magro AJ, Murakami MT, Marcussi S, Soares AM, Arni RK, Fontes MR. Crystal structure of an acidic platelet aggregation inhibitor and hypotensive phospholipase A2 in the monomeric and dimeric states: insights into its oligomeric state. Biochem Biophys Res Commun. 2004 Oct 8;323(1):24-31. PMID:15351695 doi:10.1016/j.bbrc.2004.08.046
Categories: Bothrops jararacussu | Fontes, M R. | Magro, A J. | Soares, A M. | Takeda, A A. | Acidic phospholipase a2 | Bothrops jararacussu venom | Dimeric phospholipase a2 | Hydrolase | Oligomeric state | P-bromophenacyl bromide | Phospholipase a2 inhibition | Platelet aggregation and hypotensive effect