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1ptu

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Image:1ptu.png

Template:STRUCTURE 1ptu

Contents

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (DADEPYL-NH2)

Template:ABSTRACT PUBMED 7540771

About this Structure

1ptu is a 2 chain structure with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.

See Also

Reference

  • Jia Z, Barford D, Flint AJ, Tonks NK. Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science. 1995 Jun 23;268(5218):1754-8. PMID:7540771
  • Zhang YL, Yao ZJ, Sarmiento M, Wu L, Burke TR Jr, Zhang ZY. Thermodynamic study of ligand binding to protein-tyrosine phosphatase 1B and its substrate-trapping mutants. J Biol Chem. 2000 Nov 3;275(44):34205-12. PMID:10952978 doi:10.1074/jbc.M004490200

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