2db3

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spinqualitylabelsall models PDB ID 2db3 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2db3, resolution 2.20Å ()
Ligands:	,
Gene:	VASA (Drosophila melanogaster)
Activity:	Adenosinetriphosphatase, with EC number 3.6.1.3
Structural annotation: Resources: InterPro : Ipr014014, Ipr014021, Ipr014001, Ipr011545, Ipr000629, Ipr001650 Pfam : PF00271, PF00270 UniProt : P09052
Functional annotation: Cellular component: polar granule Biological process: germarium-derived oocyte fate determination germarium-derived egg chamber formation pole plasm RNA localization positive regulation of oskar mRNA translation cell differentiation positive regulation of translation intracellular mRNA localization dorsal appendage formation multicellular organismal development karyosome formation oocyte anterior/posterior axis determination oogenesis pole plasm assembly germ-line cyst formation regulation of oskar mRNA translation mRNA polyadenylation Molecular function: helicase activity nucleotide binding protein binding ATP-dependent helicase activity RNA binding nucleic acid binding RNA helicase activity ATP binding hydrolase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB, TOPSAN
Coordinates:	save as pdb, mmCIF, xml

Contents 1 Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa 2 About this Structure 3 See Also 4 Reference

Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa

Template:ABSTRACT PUBMED 16630817

About this Structure

2db3 is a 8 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

See Also

• Helicase

Reference

• Sengoku T, Nureki O, Nakamura A, Kobayashi S, Yokoyama S. Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell. 2006 Apr 21;125(2):287-300. PMID:16630817 doi:10.1016/j.cell.2006.01.054
• Sengoku T, Nureki O, Dohmae N, Nakamura A, Yokoyama S. Crystallization and preliminary X-ray analysis of the helicase domains of Vasa complexed with RNA and an ATP analogue. Acta Crystallogr D Biol Crystallogr. 2004 Feb;60(Pt 2):320-2. Epub 2004, Jan 23. PMID:14747711 doi:10.1107/S0907444903025897