2bag

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Template:STRUCTURE 2bag

Contents 1 3D Structure of Torpedo californica acetylcholinesterase complexed with Ganstigmine 2 About this Structure 3 See Also 4 Reference

3D Structure of Torpedo californica acetylcholinesterase complexed with Ganstigmine

Template:ABSTRACT PUBMED 16913695

About this Structure

2bag is a 1 chain structure with sequence from Torpedo californica. Full crystallographic information is available from OCA.

See Also

• Acetylcholinesterase

Reference

• Bartolucci C, Siotto M, Ghidini E, Amari G, Bolzoni PT, Racchi M, Villetti G, Delcanale M, Lamba D. Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819). J Med Chem. 2006 Aug 24;49(17):5051-8. PMID:16913695 doi:http://dx.doi.org/10.1021/jm060293s
• Bartolucci C, Perola E, Cellai L, Brufani M, Lamba D. "Back door" opening implied by the crystal structure of a carbamoylated acetylcholinesterase. Biochemistry. 1999 May 4;38(18):5714-9. PMID:10231521 doi:http://dx.doi.org/10.1021/bi982723p
• Bar-On P, Millard CB, Harel M, Dvir H, Enz A, Sussman JL, Silman I. Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine. Biochemistry. 2002 Mar 19;41(11):3555-64. PMID:11888271