2vw5

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Template:STRUCTURE 2vw5

Contents 1 STRUCTURE OF THE HSP90 INHIBITOR 7-O-CARBAMOYLPREMACBECIN BOUND TO THE N- TERMINUS OF YEAST HSP90 2 About this Structure 3 See Also 4 Reference

STRUCTURE OF THE HSP90 INHIBITOR 7-O-CARBAMOYLPREMACBECIN BOUND TO THE N- TERMINUS OF YEAST HSP90

Template:ABSTRACT PUBMED 18800759

About this Structure

2vw5 is a 4 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

See Also

• Heat Shock Proteins

Reference

• Zhang MQ, Gaisser S, Nur-E-Alam M, Sheehan LS, Vousden WA, Gaitatzis N, Peck G, Coates NJ, Moss SJ, Radzom M, Foster TA, Sheridan RM, Gregory MA, Roe SM, Prodromou C, Pearl L, Boyd SM, Wilkinson B, Martin CJ. Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors. J Med Chem. 2008 Sep 25;51(18):5494-7. PMID:18800759 doi:10.1021/jm8006068