3cso

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Template:STRUCTURE 3cso

Contents 1 HCV Polymerase in complex with a 1,5 Benzodiazepine inhibitor 2 About this Structure 3 See Also 4 Reference

HCV Polymerase in complex with a 1,5 Benzodiazepine inhibitor

Template:ABSTRACT PUBMED 18852280

About this Structure

3cso is a 2 chain structure with sequence from Hepatitis c virus isolate hc-j4. Full crystallographic information is available from OCA.

See Also

• RNA polymerase

Reference

• Nyanguile O, Pauwels F, Van den Broeck W, Boutton CW, Quirynen L, Ivens T, van der Helm L, Vandercruyssen G, Mostmans W, Delouvroy F, Dehertogh P, Cummings MD, Bonfanti JF, Simmen KA, Raboisson P. 1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors. Antimicrob Agents Chemother. 2008 Dec;52(12):4420-31. Epub 2008 Oct 13. PMID:18852280 doi:10.1128/AAC.00669-08