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3ds6

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Revision as of 13:00, 20 October 2012 by OCA (Talk | contribs)
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Image:3ds6.png

Template:STRUCTURE 3ds6

Contents

P38 complex with a phthalazine inhibitor

Template:ABSTRACT PUBMED 18817365

About this Structure

3ds6 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Herberich B, Cao GQ, Chakrabarti PP, Falsey JR, Pettus L, Rzasa RM, Reed AB, Reichelt A, Sham K, Thaman M, Wurz RP, Xu S, Zhang D, Hsieh F, Lee MR, Syed R, Li V, Grosfeld D, Plant MH, Henkle B, Sherman L, Middleton S, Wong LM, Tasker AS. Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold. J Med Chem. 2008 Sep 26. PMID:18817365 doi:10.1021/jm8005417
  • Pettus LH, Xu S, Cao GQ, Chakrabarti PP, Rzasa RM, Sham K, Wurz RP, Zhang D, Middleton S, Henkle B, Plant MH, Saris CJ, Sherman L, Wong LM, Powers DA, Tudor Y, Yu V, Lee MR, Syed R, Hsieh F, Tasker AS. 3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinase. J Med Chem. 2008 Oct 23;51(20):6280-92. Epub 2008 Sep 26. PMID:18817364 doi:10.1021/jm8005405

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