From Proteopedia
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| 1hzh, resolution 2.70Å ()
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| Ligands:
| , , , ,
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| Structural annotation:
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| Resources:
| CATH : 1Hzhh04, 1Hzhh03, 1Hzhh02, 1Hzhh01, 1Hzhk04, 1Hzhk03, 1Hzhk01, 1Hzhk02, 1Hzhl02, 1Hzhl01, 1Hzhm02, 1Hzhm01
SCOP : d1hzhh4, d1hzhh2, d1hzhh1, d1hzhh3, d1hzhk3, d1hzhk1, d1hzhk4, d1hzhk2, d1hzhl2, d1hzhl1, d1hzhm2, d1hzhm1
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| Resources:
| FirstGlance, OCA, RCSB, PDBsum
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| Coordinates:
| save as pdb, mmCIF, xml
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CRYSTAL STRUCTURE OF THE INTACT HUMAN IGG B12 WITH BROAD AND POTENT ACTIVITY AGAINST PRIMARY HIV-1 ISOLATES: A TEMPLATE FOR HIV VACCINE DESIGN
Template:ABSTRACT PUBMED 11498595
About this Structure
1hzh is a 4 chain structure with sequence from Homo sapiens. The September 2001 RCSB PDB Molecule of the Month feature on Antibodies by David S. Goodsell is 10.2210/rcsb_pdb/mom_2001_9. Full crystallographic information is available from OCA.
See Also
Reference
- Saphire EO, Parren PW, Pantophlet R, Zwick MB, Morris GM, Rudd PM, Dwek RA, Stanfield RL, Burton DR, Wilson IA. Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design. Science. 2001 Aug 10;293(5532):1155-9. PMID:11498595 doi:10.1126/science.1061692
- Saphire EO, Stanfield RL, Crispin MD, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. Contrasting IgG structures reveal extreme asymmetry and flexibility. J Mol Biol. 2002 May 24;319(1):9-18. PMID:12051932 doi:10.1016/S0022-2836(02)00244-9
- Saphire EO, Stanfield RL, Crispin MD, Morris G, Zwick MB, Pantophlet RA, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design. Adv Exp Med Biol. 2003;535:55-66. PMID:14714888
