1hkq
From Proteopedia
PPS10 PLASMID DNA REPLICATION INITIATOR PROTEIN REPA. REPLICATION INACTIVE, DIMERIC N-TERMINAL DOMAIN.
About this Structure
1hkq is a 2 chain structure with sequence from Pseudomonas savastanoi. Full crystallographic information is available from OCA.
Reference
- Forest KT, Filutowicz MS. Remodeling of replication initiator proteins. Nat Struct Biol. 2003 Jul;10(7):496-8. PMID:12825085 doi:10.1038/nsb0703-496
- Diaz-Lopez T, Lages-Gonzalo M, Serrano-Lopez A, Alfonso C, Rivas G, Diaz-Orejas R, Giraldo R. Structural changes in RepA, a plasmid replication initiator, upon binding to origin DNA. J Biol Chem. 2003 May 16;278(20):18606-16. Epub 2003 Mar 7. PMID:12637554 doi:10.1074/jbc.M212024200
- Giraldo R. Common domains in the initiators of DNA replication in Bacteria, Archaea and Eukarya: combined structural, functional and phylogenetic perspectives. FEMS Microbiol Rev. 2003 Jan;26(5):533-54. PMID:12586394
- Giraldo R, Andreu JM, Diaz-Orejas R. Protein domains and conformational changes in the activation of RepA, a DNA replication initiator. EMBO J. 1998 Aug 3;17(15):4511-26. PMID:9687517 doi:10.1093/emboj/17.15.4511
- Giraldo R, Fernandez-Tornero C, Evans PR, Diaz-Orejas R, Romero A. A conformational switch between transcriptional repression and replication initiation in the RepA dimerization domain. Nat Struct Biol. 2003 Jul;10(7):565-71. PMID:12766757 doi:http://dx.doi.org/10.1038/nsb937
