1mx5

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spinqualitylabelsall models PDB ID 1mx5 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1mx5, resolution 2.80Å ()
Ligands:	, , , ,
Activity:	Carboxylesterase, with EC number 3.1.1.1
Related:	1mx1, 1mx9
Structural annotation: Resources: CATH : 1Mx5A00, 1Mx5B00, 1Mx5C00, 1Mx5D00, 1Mx5E00, 1Mx5F00 InterPro : Ipr002018 Pfam : PF00135 SCOP : d1mx5a_, d1mx5b_, d1mx5c_, d1mx5d_, d1mx5e_, d1mx5f_ UniProt : P23141
Functional annotation: Cellular component: endoplasmic reticulum extracellular space Biological process: response to toxin metabolic process Molecular function: carboxylesterase activity hydrolase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 Crystal Structure of Human Liver Carboxylesterase in complexed with homatropine, a cocaine analogue 2 About this Structure 3 See Also 4 Reference

Crystal Structure of Human Liver Carboxylesterase in complexed with homatropine, a cocaine analogue

Template:ABSTRACT PUBMED 12679808

About this Structure

1mx5 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Carboxylesterase

Reference

• Bencharit S, Morton CL, Xue Y, Potter PM, Redinbo MR. Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme. Nat Struct Biol. 2003 May;10(5):349-56. PMID:12679808 doi:10.1038/nsb919