1mim

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Template:STRUCTURE 1mim

Contents

IGG FAB FRAGMENT (CD25-BINDING)

Template:ABSTRACT PUBMED 15299676

Disease

[IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.[1]

About this Structure

1mim is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mikol V. Structure of the fab fragment of SDZ CHI621: a chimeric antibody against CD25. Acta Crystallogr D Biol Crystallogr. 1996 May 1;52(Pt 3):534-42. PMID:15299676 doi:10.1107/S0907444996000704
  1. ↑ Stavnezer-Nordgren J, Kekish O, Zegers BJ. Molecular defects in a human immunoglobulin kappa chain deficiency. Science. 1985 Oct 25;230(4724):458-61. PMID:3931219

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