1w1d
From Proteopedia
CRYSTAL STRUCTURE OF THE PDK1 PLECKSTRIN HOMOLOGY (PH) DOMAIN BOUND TO INOSITOL (1,3,4,5)-TETRAKISPHOSPHATE
Template:ABSTRACT PUBMED 15457207
About this Structure
1w1d is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Komander D, Fairservice A, Deak M, Kular GS, Prescott AR, Peter Downes C, Safrany ST, Alessi DR, van Aalten DM. Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates. EMBO J. 2004 Oct 13;23(20):3918-28. Epub 2004 Sep 30. PMID:15457207 doi:10.1038/sj.emboj.7600379
- Komander D, Deak M, Morrice N, van Aalten DM. Purification, crystallization and preliminary X-ray diffraction of a proteolytic fragment of PDK1 containing the pleckstrin homology domain. Acta Crystallogr D Biol Crystallogr. 2004 Feb;60(Pt 2):314-6. Epub 2004, Jan 23. PMID:14747709 doi:10.1107/S0907444903028518
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Aalten, D M.F Van. | Alessi, D R. | Deak, M. | Komander, D. | Inositol phosphate | Pdk1 | Phosphoinositide | Phosphoinositide dependent protein kinase 1 | Pi3-kinase | Pkb | Pleckstrin homology domain | Serine/threonine protein kinase | Signal transduction | Transferase
