1z8g

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Image:1z8g.png

Template:STRUCTURE 1z8g

Crystal structure of the extracellular region of the transmembrane serine protease hepsin with covalently bound preferred substrate.

Template:ABSTRACT PUBMED 15839837

About this Structure

1z8g is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Herter S, Piper DE, Aaron W, Gabriele T, Cutler G, Cao P, Bhatt AS, Choe Y, Craik CS, Walker N, Meininger D, Hoey T, Austin RJ. Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers. Biochem J. 2005 Aug 15;390(Pt 1):125-36. PMID:15839837 doi:10.1042/BJ20041955

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