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1ugv
From Proteopedia
Contents |
Solution structure of the SH3 domain of human olygophrein-1 like protein (KIAA0621)
Disease
[RHG26_HUMAN] Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:607785]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient.
Function
[RHG26_HUMAN] GTPase-activating protein for RHOA and CDC42.
About this Structure
1ugv is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Categories: Homo sapiens | Aoki, M. | Hayashi, F. | Hirota, H. | Inoue, K. | Inoue, M. | Kigawa, T. | Kikuno, R. | Matsuda, T. | Matsuo, Y. | Nagase, T. | Nakayama, M. | Ohara, O. | Osanai, T. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Seki, E. | Shirouzu, M. | Tanaka, A. | Terada, T. | Yabuki, T. | Yokoyama, S. | Yoshida, M. | Beta barrel | Graf protein | Protein binding | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic
