1vec

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Template:STRUCTURE 1vec

Contents

Crystal structure of the N-terminal domain of rck/p54, a human DEAD-box protein

Template:ABSTRACT PUBMED 16611246

Disease

[DDX6_HUMAN] Note=A chromosomal aberration involving DDX6 may be a cause of hematopoietic tumors such as B-cell lymphomas. Translocation t(11;14)(q23;q32).

Function

[DDX6_HUMAN] In the process of mRNA degradation, may play a role in mRNA decapping.

About this Structure

1vec is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Matsui T, Hogetsu K, Usukura J, Sato T, Kumasaka T, Akao Y, Tanaka N. Structural insight of human DEAD-box protein rck/p54 into its substrate recognition with conformational changes. Genes Cells. 2006 Apr;11(4):439-52. PMID:16611246 doi:10.1111/j.1365-2443.2006.00951.x

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