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2azm

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Image:2azm.png

Template:STRUCTURE 2azm

Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX

Template:ABSTRACT PUBMED 16377563

About this Structure

2azm is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, Jackson SP. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell. 2005 Dec 29;123(7):1213-26. PMID:16377563 doi:10.1016/j.cell.2005.09.038

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