2eu0

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Template:STRUCTURE 2eu0

The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide

Template:ABSTRACT PUBMED 16436281

About this Structure

2eu0 is a 2 chain structure with sequence from Mus musculus. Full experimental information is available from OCA.

Reference

  • Pletneva EV, Sundd M, Fulton DB, Andreotti AH. Molecular details of Itk activation by prolyl isomerization and phospholigand binding: the NMR structure of the Itk SH2 domain bound to a phosphopeptide. J Mol Biol. 2006 Mar 24;357(2):550-61. Epub 2006 Jan 18. PMID:16436281 doi:http://dx.doi.org/10.1016/j.jmb.2005.12.073
  • Mallis RJ, Brazin KN, Fulton DB, Andreotti AH. Structural characterization of a proline-driven conformational switch within the Itk SH2 domain. Nat Struct Biol. 2002 Dec;9(12):900-5. PMID:12402030 doi:http://dx.doi.org/10.1038/nsb864

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