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2jc2

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Image:2jc2.png

Template:STRUCTURE 2jc2

THE CRYSTAL STRUCTURE OF THE NATURAL F112L HUMAN SORCIN MUTANT

Template:ABSTRACT PUBMED 17699613

About this Structure

2jc2 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Franceschini S, Ilari A, Verzili D, Zamparelli C, Antaramian A, Rueda A, Valdivia HH, Chiancone E, Colotti G. Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor. FASEB J. 2008 Jan;22(1):295-306. Epub 2007 Aug 15. PMID:17699613 doi:10.1096/fj.07-8988com
  • Ilari A, Johnson KA, Nastopoulos V, Verzili D, Zamparelli C, Colotti G, Tsernoglou D, Chiancone E. The crystal structure of the sorcin calcium binding domain provides a model of Ca2+-dependent processes in the full-length protein. J Mol Biol. 2002 Mar 29;317(3):447-58. PMID:11922676 doi:10.1006/jmbi.2002.5417
  • Xie X, Dwyer MD, Swenson L, Parker MH, Botfield MC. Crystal structure of calcium-free human sorcin: a member of the penta-EF-hand protein family. Protein Sci. 2001 Dec;10(12):2419-25. PMID:11714909

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