2j8u

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Template:STRUCTURE 2j8u

Contents 1 LARGE CDR3A LOOP ALTERATION AS A FUNCTION OF MHC MUTATION. 2 Function 3 About this Structure 4 See Also 5 Reference

LARGE CDR3A LOOP ALTERATION AS A FUNCTION OF MHC MUTATION.

Template:ABSTRACT PUBMED 17825839

Function

[1A02_HUMAN] Involved in the presentation of foreign antigens to the immune system.

About this Structure

2j8u is a 10 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

See Also

• Beta-2 microglobulin
• Major histocompatibility complex
• T-cell receptor

Reference

• Miller PJ, Pazy Y, Conti B, Riddle D, Appella E, Collins EJ. Single MHC mutation eliminates enthalpy associated with T cell receptor binding. J Mol Biol. 2007 Oct 19;373(2):315-27. Epub 2007 Jul 26. PMID:17825839 doi:10.1016/j.jmb.2007.07.028