2fum

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Image:2fum.png

Template:STRUCTURE 2fum

Catalytic domain of protein kinase PknB from Mycobacterium tuberculosis in complex with mitoxantrone

Template:ABSTRACT PUBMED 16674948

About this Structure

2fum is a 4 chain structure with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

Reference

  • Wehenkel A, Fernandez P, Bellinzoni M, Catherinot V, Barilone N, Labesse G, Jackson M, Alzari PM. The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria. FEBS Lett. 2006 May 29;580(13):3018-22. Epub 2006 Apr 27. PMID:16674948 doi:10.1016/j.febslet.2006.04.046

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