2wwj

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Image:2wwj.png

Template:STRUCTURE 2wwj

STRUCTURE OF JMJD2A COMPLEXED WITH INHIBITOR 10A

Template:ABSTRACT PUBMED 20088513

About this Structure

2wwj is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rose NR, Woon EC, Kingham GL, King ON, Mecinovic J, Clifton IJ, Ng SS, Talib-Hardy J, Oppermann U, McDonough MA, Schofield CJ. Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches. J Med Chem. 2010 Feb 25;53(4):1810-8. PMID:20088513 doi:10.1021/jm901680b

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