2vya
From Proteopedia
CRYSTAL STRUCTURE OF FATTY ACID AMIDE HYDROLASE CONJUGATED WITH THE DRUG-LIKE INHIBITOR PF-750
Template:ABSTRACT PUBMED 18753625
About this Structure
2vya is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Mileni M, Johnson DS, Wang Z, Everdeen DS, Liimatta M, Pabst B, Bhattacharya K, Nugent RA, Kamtekar S, Cravatt BF, Ahn K, Stevens RC. Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12820-4. Epub 2008 Aug 27. PMID:18753625
Categories: Amidase | Rattus norvegicus | Ahn, K. | Bhattacharya, K. | Cravatt, B F. | Everdeen, D S. | Johnson, D S. | Kamtekar, S. | Liimatta, M. | Mileni, M. | Nugent, R A. | Pabst, B. | Stevens, R C. | Wang, Z. | Chimera | Covalent | Drug- like | Endoplasmic reticulum | Faah | Fatty acid amide hydrolyse | Golgi apparatus | Humanized | Hydrolase | Inhibitor | Membrane | Transmembrane
