2cfa

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Template:STRUCTURE 2cfa

Contents

Structure of viral flavin-dependant thymidylate synthase ThyX

Template:ABSTRACT PUBMED 16707489

Function

[THYX_PBCV1] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity).

About this Structure

2cfa is a 2 chain structure with sequence from Paramecium bursaria chlorella virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  • Graziani S, Bernauer J, Skouloubris S, Graille M, Zhou CZ, Marchand C, Decottignies P, van Tilbeurgh H, Myllykallio H, Liebl U. Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX. J Biol Chem. 2006 Aug 18;281(33):24048-57. Epub 2006 May 17. PMID:16707489 doi:10.1074/jbc.M600745200

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