1e5g

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Template:STRUCTURE 1e5g

Contents 1 Solution structure of central CP module pair of a pox virus complement inhibitor 2 Function 3 About this Structure 4 Reference

Solution structure of central CP module pair of a pox virus complement inhibitor

Template:ABSTRACT PUBMED 11243823

Function

[VCP_VACCC] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b.

About this Structure

1e5g is a 1 chain structure with sequence from Vaccinia virus copenhagen. Full experimental information is available from OCA.

Reference

• Henderson CE, Bromek K, Mullin NP, Smith BO, Uhrin D, Barlow PN. Solution structure and dynamics of the central CCP module pair of a poxvirus complement control protein. J Mol Biol. 2001 Mar 16;307(1):323-39. PMID:11243823 doi:10.1006/jmbi.2000.4477