2zpp

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Template:STRUCTURE 2zpp

Contents 1 Neutron crystal structure of cubic insulin at pD9 2 Function 3 About this Structure 4 See Also 5 Reference

Neutron crystal structure of cubic insulin at pD9

Template:ABSTRACT PUBMED 18725203

Function

[INS_PIG] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

About this Structure

2zpp is a 2 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.

See Also

• Molecular Playground/Insulin

Reference

• Ishikawa T, Chatake T, Morimoto Y, Maeda M, Kurihara K, Tanaka I, Niimura N. An abnormal pK(a) value of internal histidine of the insulin molecule revealed by neutron crystallographic analysis. Biochem Biophys Res Commun. 2008 Nov 7;376(1):32-5. Epub 2008 Aug 24. PMID:18725203 doi:10.1016/j.bbrc.2008.08.071