1azt

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Template:STRUCTURE 1azt

Contents

GS-ALPHA COMPLEXED WITH GTP-GAMMA-S

Template:ABSTRACT PUBMED 9395396

Function

[GNAS2_BOVIN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli.

About this Structure

1azt is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  • Sunahara RK, Tesmer JJ, Gilman AG, Sprang SR. Crystal structure of the adenylyl cyclase activator Gsalpha. Science. 1997 Dec 12;278(5345):1943-7. PMID:9395396

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OCA

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