2bq1

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Template:STRUCTURE 2bq1

Contents 1 Ribonucleotide reductase class 1b holocomplex R1E,R2F from Salmonella typhimurium 2 Function 3 About this Structure 4 See Also 5 Reference

Ribonucleotide reductase class 1b holocomplex R1E,R2F from Salmonella typhimurium

Template:ABSTRACT PUBMED 16631785

Function

[RIR4_SALTY] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2F contains the tyrosyl radical required for catalysis.

About this Structure

2bq1 is a 4 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhimurium. Full crystallographic information is available from OCA.

See Also

• Ribonucleotide reductase

Reference

• Uppsten M, Farnegardh M, Domkin V, Uhlin U. The first holocomplex structure of ribonucleotide reductase gives new insight into its mechanism of action. J Mol Biol. 2006 Jun 2;359(2):365-77. Epub 2006 Mar 31. PMID:16631785 doi:10.1016/j.jmb.2006.03.035