1s6l

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Template:STRUCTURE 1s6l

Contents 1 Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system 2 Function 3 About this Structure 4 Reference

Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system

Template:ABSTRACT PUBMED 15222745

Function

[MERB_ECOLI] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity).

About this Structure

1s6l is a 1 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

• Di Lello P, Benison GC, Valafar H, Pitts KE, Summers AO, Legault P, Omichinski JG. NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyase involved in the bacterial mercury resistance system. Biochemistry. 2004 Jul 6;43(26):8322-32. PMID:15222745 doi:10.1021/bi049669z
• Di Lello P, Benison GC, Omichinski JG, Legault P. 1H, 15N, and 13C resonance assignment of the 23 kDa organomercurial lyase MerB in its free and mercury-bound forms. J Biomol NMR. 2004 Jul;29(3):457-8. PMID:15213467 doi:10.1023/B:JNMR.0000032559.32474.a1