2pc8

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Template:STRUCTURE 2pc8

Contents

E292Q mutant of EXO-B-(1,3)-Glucanase from Candida Albicans in complex with two separately bound glucopyranoside units at 1.8 A

Template:ABSTRACT PUBMED 20875088

Function

[EXG_CANAL] Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase.

About this Structure

2pc8 is a 1 chain structure with sequence from Candida albicans. Full crystallographic information is available from OCA.

Reference

  • Patrick WM, Nakatani Y, Cutfield SM, Sharpe ML, Ramsay RJ, Cutfield JF. Carbohydrate binding sites in Candida albicans exo-beta-1,3-glucanase and the role of the Phe-Phe 'clamp' at the active site entrance. FEBS J. 2010 Sep 10. doi: 10.1111/j.1742-4658.2010.07869.x. PMID:20875088 doi:10.1111/j.1742-4658.2010.07869.x

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