2w0n

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Template:STRUCTURE 2w0n

Contents

Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS

Template:ABSTRACT PUBMED 18820688

Function

[DCUS_ECOLI] Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation.

About this Structure

2w0n is a 1 chain structure with sequence from Escherichia coli bl21(de3). Full experimental information is available from OCA.

Reference

  • Etzkorn M, Kneuper H, Dunnwald P, Vijayan V, Kramer J, Griesinger C, Becker S, Unden G, Baldus M. Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS. Nat Struct Mol Biol. 2008 Oct;15(10):1031-9. Epub 2008 Sep 28. PMID:18820688 doi:10.1038/nsmb.1493

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