2jfd

From Proteopedia

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Template:STRUCTURE 2jfd

Contents 1 Structure of the MAT domain of human FAS 2 Function 3 About this Structure 4 See Also 5 Reference

Structure of the MAT domain of human FAS

Template:ABSTRACT PUBMED 19549604

Function

[FAS_HUMAN] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.

About this Structure

2jfd is a 4 chain structure with sequence from Human. Full crystallographic information is available from OCA.

See Also

• Fatty acid synthase

Reference

• Bunkoczi G, Misquitta S, Wu X, Lee WH, Rojkova A, Kochan G, Kavanagh KL, Oppermann U, Smith S. Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases. Chem Biol. 2009 Jun 26;16(6):667-75. doi: 10.1016/j.chembiol.2009.04.011. PMID:19549604 doi:http://dx.doi.org/10.1016/j.chembiol.2009.04.011