2zyg

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Template:STRUCTURE 2zyg

Contents 1 Apo-form of dimeric 6-phosphogluconate dehydrogenase 2 Function 3 About this Structure 4 See Also 5 Reference

Apo-form of dimeric 6-phosphogluconate dehydrogenase

Template:ABSTRACT PUBMED 19686854

Function

[Q762L5_KLEPN] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity).[PIRNR:PIRNR000109]

About this Structure

2zyg is a 2 chain structure with sequence from "bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886. Full crystallographic information is available from OCA.

See Also

• 6-phosphogluconate dehydrogenase

Reference

• Chen YY, Ko TP, Chen WH, Lo LP, Lin CH, Wang AH. Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism. J Struct Biol. 2010 Jan;169(1):25-35. Epub 2009 Aug 15. PMID:19686854 doi:10.1016/j.jsb.2009.08.006